BDBM25279 BPH-608::bisphosphonate, 31::{1-hydroxy-2-[3-(3-phenylphenyl)phenyl]-1-phosphonoethyl}phosphonic acid

SMILES OC(Cc1cccc(c1)-c1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=YXQQNSYZOQHKHD-UHFFFAOYSA-N

Data  2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25279   

TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego

LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)
Affinity DataIC50:  1.80E+4nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed